AVA-311
AVA-311 is being developed for the treatment of Juvenile X-linked Retinoschisis (XLRS), an inherited retinal disease that occurs almost exclusively in males caused by mutations in the RS1gene located on the X chromosome. AVA-311 is comprised of an optimized AAV vector using Avalanche’s directed evolution technology that intravitreally delivers the RS1 gene in the 83 eye to potentially achieve a functional cure for patients.
In May 2014, Avalanche signed a collaboration agreement with Regeneron for the development of AVA-311.
